Ionotropic glutamate receptors: still a target for neuroprotection in brain ischemia? insights from in vitro studies
Although experimental studies have widely shown that the pharmacological blockade of ionotropic glutamate receptors reduces ischemic damage, clinical trials with classical AMPA and NMDA glutamate receptor antagonists have provided negative results.To address the involvement read more of ionotropic glutamate receptors in ischemic damage, corticostri