IONOTROPIC GLUTAMATE RECEPTORS: STILL A TARGET FOR NEUROPROTECTION IN BRAIN ISCHEMIA? INSIGHTS FROM IN VITRO STUDIES

Ionotropic glutamate receptors: still a target for neuroprotection in brain ischemia? insights from in vitro studies

Although experimental studies have widely shown that the pharmacological blockade of ionotropic glutamate receptors reduces ischemic damage, clinical trials with classical AMPA and NMDA glutamate receptor antagonists have provided negative results.To address the involvement read more of ionotropic glutamate receptors in ischemic damage, corticostri

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Tropism and molecular pathogenesis of canine distemper virus

Abstract Background Canine distemper virus (CDV), currently termed Canine morbillivirus, is an extremely contagious disease that affects dogs.It is identified as a multiple cell tropism pathogen, and its host range includes a vast array of species.As a member of Mononegavirales, CDV has a negative, single-stranded RNA genome, which encodes eight pr

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Quantitative and qualitative evaluation of the impact of the G2 enhancer, bead sizes and lysing tubes on the bacterial community composition during DNA extraction from recalcitrant soil core samples based on community sequencing and qPCR.

Soil DNA extraction encounters numerous challenges that can affect both yield and purity of the recovered DNA.Clay particles lead to reduced DNA extraction efficiency, and PCR inhibitors from the soil matrix can negatively affect downstream read more analyses when applying DNA sequencing.Further, these effects impede molecular analysis of bacterial

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